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ORIGINAL ARTICLE
Year : 2020  |  Volume : 4  |  Issue : 3  |  Page : 463-467

Albuminuria and its relation to severity of coronary artery disease detected by angiography in type 2 diabetic patients


SYNTAX score Department of Cardiology, Al Azhar University, Cairo, Egypt

Correspondence Address:
Eman E.A Elwafa
SYNTAX score Department of Cardiology, Al Azhar University, Cairo, Tanta Al Gharbia
Egypt
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/sjamf.sjamf_70_20

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Background Diabetes mellitus (DM) is one of the most potent risk factors for coronary artery disease (CAD). Consequently, the diagnosis of CAD in diabetic patients is very important as early as possible. Microalbuminuria is a strong and independent indicator of increased cardiovascular risk among individuals with and without diabetes. Aim The study aimed to assess the relation between the degree of albuminuria and the angiographic severity of CAD in patients with type 2 DM. Patients and methods A total of 40 patients with type 2 DM who were referred for elective coronary angiography owing to a suspected CAD were included in the study. Urinary albumin-creatinine ratio (UACR) was calculated for all patients, and the severity of CAD was assessed using the SYNTAX score. All patients were assessed by conventional and 2-D speckle tracking echocardiography. Results The study population comprised 19 (41.5%) males and 21 (58.5%) females. Their mean age was 53.5±8.7 years. Patients were classified into two groups based on the level of UACR; group 1 included patients with UACR less than 30 mg/g (19 patients), and group 2 included patients with UACR greater than or equal to 30 mg/g (21 patients). The study revealed significantly higher SYNTAX score in patients in group 2 compared with patients in group 1 (P=0.02) and significantly lower left ventricular global longitudinal strain in patients in group 2 compared with patients in group 1 (P=0.016). There was also a weak positive correlation between UACR and SYNTAX score and the duration of DM (r=0.395 and 0.399, respectively). Conclusion Microalbuminuria can be used as a predictor of the presence and severity of CAD in type II DM.


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